Trihexyphenidyl uses: Parkinson’s Disease and Others

Trihexyphenidyl, an antiparkinsonian agent has been prescribed for decades prevents efferent impulses in parasympathetically innervated structures like smooth muscles, salivary glands, and eyes, i.e., it is a antispasmodic drug. Unlike Artane, the trihexyphenidyl brand name drug, the generic version is available as 2 mg tablets on for a lot cheaper.

While the drug can’t cure Parkinson’s Disease, it offers considerable improvement in symptoms. Approximately 50% – 75% patients with Parkinson’s Disease gain relief with Trihexyphenidyl, with about 20% – 30% alleviation in symptoms.

Some antipsychotic medications used to treat mental disorders such as schizophrenia may cause side effects resembling Parkinson’s disease symptoms. Trihexyphenidyl treats Parkinsonian side effects such as, tremors in muscles, difficulty with voluntary movements, and poor muscle tone.

Trihexyphenidyl is also prescribed for children between 2 to 17 years old to treat dystonia in cerebral palsy.

If a patient experiences the side effects mentioned below, then he/she must seek emergency medical attention or contact the prescribing doctor at once:

  • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
  • fever;
  • fast or irregular heartbeats;
  • anxiety, hallucinations, confusion, agitation, hyperactivity, or loss of consciousness;
  • seizures;
  • eye pain; or
  • rash.

Inform your healthcare provider when you are prescribed Trihexyphenidyl and are already taking any of these drugs: Amitriptyline , Imipramine , Trimipramine , Desipramine , Nortriptyline , Protriptyline , Amoxapine , and Doxepin, as the effects/side effects of Trihexyphenidyl are amplified.
Patients with liver or kidney disorders, hypertension, etc., need to inform their healthcare providers when Trihexyphenidyl is prescribed.

Over one million Americans live with Parkinson’s disease and 60,000 are diagnosed each year. The cost of Parkinson’s disease is approximately $25 billion per year in the USA, including the cost of treatment, social security payments and lost income from inability to work. Medicines for patients with PD average to about $2,500 a year. helps patients living with Parkinson’s Disease sustain their prescription medicines by offering generic prescription and OTC drugs at much lower prices than their branded versions, and are bio-equivalent and just as effective.


No Comments »

No comments yet.

RSS feed for comments on this post. TrackBack URL

Leave a comment

You must be logged in to post a comment.