The researchers randomly assigned more than 12,000 heart attack survivors to take either placebo pills or vitamin B12 (1 mg daily) and folic acid (2 mg). Then they followed the patients for almost seven years to see if the vitamins would protect them.
About a quarter of the patients on placebo pills suffered a heart attack or a stroke over the follow-up period. In the vitamin group, slightly more people did so, despite their considerably lower homocysteine levels.
Source: http://www.reuters.com/article/idUSTRE65L6CJ20100622
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